abstract：PURPOSE OF REVIEW:Exacerbations of asthma in children are most frequently precipitated by respiratory infections with a seasonal pattern. However, management takes little account of the underlying infective or other precipitant abnormality. RECENT FINDINGS:Interactions between environmental triggers, the airway microb...

journal_title：Current opinion in pulmonary medicine

authors： Cook J,Saglani S

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to evaluate the consequence of obstructive sleep apnea (OSA) in pulmonary hypertension by reviewing the current literature and understanding potential pathophysiological mechanisms. RECENT FINDINGS:Small studies have suggested a high prevalence of comorbid OSA in those ...

journal_title：Current opinion in pulmonary medicine

authors： Minic M,Ryan CM

更新日期：2015-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights the prevalence of pulmonary hypertension as a chronic complication of sickle cell disease (SCD) and its importance in the prognosis. RECENT FINDINGS:In recent years, the limitations of echocardiogram for the appropriate diagnosis of SCD-associated pulmonary hypertension have be...

journal_title：Current opinion in pulmonary medicine

authors： Fonseca G,Souza R

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the fact that primary pulmonary lymphoma (PPL) is a rare lung tumour, significant advances addressing clinical features, histological diagnosis, prognostic criteria and therapeutic management of this disease have been made within the past decade. RECENT FINDINGS:Monoclonality and phenotyping ...

journal_title：Current opinion in pulmonary medicine

authors： Cardenas-Garcia J,Talwar A,Shah R,Fein A

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Pleural effusions are a common finding in the nearly six million Americans diagnosed with heart failure. This review focuses on the historical, present and potential future trends in the management of such benign pleural effusions. RECENT FINDINGS:The management of symptomatic pleural effusions, in g...

journal_title：Current opinion in pulmonary medicine

authors： Freeman RK

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the most common infectious disease cause of death. We summarize recent findings regarding the epidemiology of CAP in adults, efficacy of vaccines against Streptococcus pneumoniae, diagnostics, and discuss the current controversy between CAP and healthcare-associat...

journal_title：Current opinion in pulmonary medicine

authors： José RJ,Periselneris JN,Brown JS

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Control of tuberculosis necessitates prompt diagnosis and access to effective treatment. We discuss the impact of a new nucleic acid amplification test to assist diagnosis and detect rifampicin resistance. Following encouraging clinical performance studies, an automated PCR-based test, the Xpert MTB/R...

journal_title：Current opinion in pulmonary medicine

authors： McNerney R,Zumla A

更新日期：2015-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Adherence to asthma therapies is poor leading to unnecessary morbidity and increased use of emergency and hospital resources. Strategies to improve adherence have not been successful. RECENT FINDINGS:Asthma adherence disease management is a clinical method to improve adherence for asthma patients. Th...

journal_title：Current opinion in pulmonary medicine

authors： Weinstein AG

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity has significant impact on asthma incidence and manifestations. The purpose of the review is to discuss recent observations regarding the association between obesity and asthma focusing on underlying mechanisms, clinical presentation, response to therapy and effect of weight reduction. RECENT ...

journal_title：Current opinion in pulmonary medicine

authors： Sivapalan P,Diamant Z,Ulrik CS

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of noninvasive ventilatory support in patients with cystic fibrosis (CF) has increased exponentially over the past 2 decades. This review examines the current knowledge and considers potential future directions for use of noninvasive ventilation in CF patients. RECENT FINDINGS:Noninvasive ven...

journal_title：Current opinion in pulmonary medicine

authors： Bright-Thomas RJ,Johnson SC

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the multiple clinical aspects of hypersomnias of central origin. Emphasis is given to the new pathophysiological pathways and treatment options described in the current literature. RECENT FINDINGS:Narcolepsy is the most recognized of the hypersomnias of central origin. Hypocretin deficien...

journal_title：Current opinion in pulmonary medicine

authors： Drakatos P,Leschziner GD

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment of hepatic hydrothorax is challenging because of its rapid symptomatic recurrence. This review will focus on potential therapeutic approaches to hepatic hydrothorax. RECENT FINDINGS:Hepatic hydrothorax is refractory to salt restriction and diuretics in approximately 25% of cases. Primary ma...

journal_title：Current opinion in pulmonary medicine

authors： Porcel JM

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims to review the geological background of environmental asbestos exposure and the distribution of asbestos-related disease (ARD) in association with naturally occurring asbestos (NOA), and discusses the potential health risks associated with exposure to non-occupational asbestos. RECEN...

journal_title：Current opinion in pulmonary medicine

authors： Bayram M,Bakan ND

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the associations between chronic obstructive pulmonary disease (COPD) and renal and hepatobiliary diseases, with emphasis on the epidemiology and clinical outcomes, along with current information on pathophysiologic mechanisms and risk factors. RECENT FINDINGS:Glomerular filtrati...

journal_title：Current opinion in pulmonary medicine

authors： Mapel D

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Severe asthma is a heterogeneous syndrome, encompassing several distinct clinical phenotypes. Different molecular and cellular pathways or endotypes determine the type of underlying airway inflammation in patients with severe asthma, which can be categorized as eosinophilic asthma (allergic and nonall...

journal_title：Current opinion in pulmonary medicine

authors： Brusselle GG,Joos G

更新日期：2014-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines the current reports, the evidence and the issues surrounding the use of non-invasive ventilation (NIV) for the treatment of chronic obstructive pulmonary disease (COPD) in both the acute and domiciliary setting. RECENT FINDINGS:With the increasing use of NIV, more recent studies ...

journal_title：Current opinion in pulmonary medicine

authors： Ramsay M,Hart N

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Survival for patients with cystic fibrosis (CF) continues to improve. The proportion of CF patients over the age of 18 years is nearly 50%, and care providers will need to better understand this patient population. Despite these improvements, young females continue to have a worse prognosis and lower ...

journal_title：Current opinion in pulmonary medicine

authors： McIntyre K

更新日期：2013-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Idiopathic pulmonary fibrosis (IPF) is a progressive, invariably fatal condition with a median survival from diagnosis of only 3 years. Despite improvements in disease understanding, challenges remain in establishing a diagnosis and predicting prognosis in individual patients. Furthermore, limited und...

journal_title：Current opinion in pulmonary medicine

authors： Maher TM

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Common variable immunodeficiency (CVID) is the most common primary immunodeficiency characterized by a deficiency of immunoglobulins. Approximately 30% of the patients develop autoimmune and granulomatous disease. Similar to sarcoidosis, granulomatous disease in CVID can potentially affect all organs,...

journal_title：Current opinion in pulmonary medicine

authors： Prasse A,Kayser G,Warnatz K

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update on the diagnosis and classification of interstitial lung disease (ILD), with a specific focus on newly described ILD subtypes and phenotypes. In addition, the strengths and limitations of the current approach to ILD diagnosis and management are discus...

journal_title：Current opinion in pulmonary medicine

authors： Ryerson CJ,Collard HR

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Lung cancer is the leading cause of cancer mortality in men and women. Most patients present with advanced disease and face significant morbidity, with many reporting distressing symptoms throughout the course of their illness. The purpose of this review is to highlight the recent studies that support...

journal_title：Current opinion in pulmonary medicine

authors： Shin J,Temel J

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Malignant pleural effusion (MPE) is common. However, regardless of the differences between patients, their underlying cancer type, and pleural fluid characteristics, management options are often limited. These have not advanced significantly over the last 80 years since pleurodesis was first described...

journal_title：Current opinion in pulmonary medicine

authors： Davies HE,Lee YC

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past few years, there have been exciting developments in bronchoscopic efforts at attaining lung volume reduction (LVR), given real and perceived risks of surgical LVR. The purpose of this review is to discuss these techniques, with special emphasis on what we have learnt in the past 1-2 years....

journal_title：Current opinion in pulmonary medicine

authors： Taneja A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is caused by a mixture of small airway disease (obstructive bronchitis) and parenchymal lung tissue destruction (emphysema). The relative contributions of these two pathologic states vary from person to person. Having the ability to phenotype patients into ...

journal_title：Current opinion in pulmonary medicine

authors： Stewart JI,Criner GJ

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma outcomes constitute the cornerstone of asthma clinical research. Despite their known importance, it has been difficult for researchers to standardize these outcomes in large part because of the heterogeneity of the disease. This review seeks to provide an overview of recent recommendations for ...

journal_title：Current opinion in pulmonary medicine

authors： Parulekar AD,Alobaidy A,Hanania NA

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to examine the evidence for the effectiveness of systemic corticosteroids in managing acute asthma in children as it relates to the timing of its administration. RECENT FINDINGS:Three themes relevant to the timing of systemic corticosteroid administration as it relates to m...

journal_title：Current opinion in pulmonary medicine

authors： Bhogal SK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:It is increasingly clear that asthma is not a single disease, but a disorder with vast heterogeneity in pathogenesis, severity, and treatment response. In this review, we discuss the present understanding of different asthma phenotypes and endotypes, and the prospects of personalized medicine for asth...

journal_title：Current opinion in pulmonary medicine

authors： Lin TY,Poon AH,Hamid Q

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Dornase alfa (Pulmozyme) is one of the most commonly used medications to treat the lung disease of cystic fibrosis (CF). As other respiratory medications have entered the clinical market, understanding the proper use and indication for dornase alfa is increasingly important. In addition, dornase alfa ...

journal_title：Current opinion in pulmonary medicine

authors： Wagener JS,Kupfer O

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnosis of idiopathic interstitial pneumonias (IIPs) requires the exclusion of, among others, concomitant connective tissue diseases (CTDs), which may present as interstitial lung disease (ILD). This review focuses on the evaluation required to separate these entities through serology, although not ...

journal_title：Current opinion in pulmonary medicine

authors： Papiris SA,Kagouridis K,Bouros D

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Ever since sarcoidosis was first described, its relationship with tuberculosis has been debated. Whereas some consider sarcoidosis and tuberculosis as two extremes of the same disease process, other researchers have negated the role of mycobacteria in causation of sarcoidosis. Whether or not linked ca...

journal_title：Current opinion in pulmonary medicine

authors： Gupta D,Agarwal R,Aggarwal AN,Jindal SK

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cancer patients with venous thromboembolism (VTE) are at increased risk of mortality. Estimating the risks for specific causes of death may help to weigh the risks and benefits of different therapeutic strategies in an individual patient. RECENT FINDINGS:In the Registro Informatizado de la Enfermedad...

journal_title：Current opinion in pulmonary medicine

authors： Trujillo-Santos J,Monreal M

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we describe the 'state-of-the-art' in our knowledge of asthma and what gaps exist, which can be exploited in the future for effective translation of our knowledge from the bench or population studies to diagnosis and therapy. RECENT FINDINGS:The advent of microbiome research has expan...

journal_title：Current opinion in pulmonary medicine

authors： Brar T,Nagaraj S,Mohapatra S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective is to discuss recent progress in our understanding of the role of the indoor environment in asthma, focusing on the special role of cat allergens. RECENT FINDINGS:Sensitization to Fel d 1 is the dominant event in inhalant responses to cat; however, there are also IgE responses to the li...

journal_title：Current opinion in pulmonary medicine

authors： Kelly LA,Erwin EA,Platts-Mills TA

更新日期：2012-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and increasing health problems in the elderly on a worldwide scale. The management of COPD in older patients presents practical diagnostic and treatment issues, which are reviewed with reference to the stable stage of the diseas...

journal_title：Current opinion in pulmonary medicine

authors： Pistelli R,Ferrara L,Misuraca C,Bustacchini S

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review looks at what is currently known about liver disease in cystic fibrosis (CF) in light of the literature over the past year, and what the ongoing challenges are from a clinical and research perspective for the optimal management of cystic fibrosis liver disease (CFLD). RECENT FINDINGS:Pati...

journal_title：Current opinion in pulmonary medicine

authors： Rowland M,Bourke B

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Respiratory infection is a major contributor to morbidity and mortality in cystic fibrosis (CF). One infection the CF community is particularly concerned about is methicillin-resistant Staphylococcus aureus (MRSA). Worldwide, the prevalence of MRSA has been rising and the impact on clinical outcomes a...

journal_title：Current opinion in pulmonary medicine

authors： Dasenbrook EC

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Isolated distal deep-vein thrombosis (iDDVT) is a distal deep-vein thrombosis (DVT) without proximal DVT or pulmonary embolism. Although its clinical significance is uncertain, its prevalence is increasing with the use of whole leg compression ultrasonography. Epidemiological data giving reported rate...

journal_title：Current opinion in pulmonary medicine

authors： Galanaud JP,Bosson JL,Quéré I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Bronchial and bronchiolar abnormalities in interstitial lung diseases (ILDs) are an issue often underestimated. However, new interstitial patterns with bronchiolar involvement are being described and the concept is still evolving. The scope of this review is to introduce a comprehensive approach to ai...

journal_title：Current opinion in pulmonary medicine

authors： Pappas K

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Pulmonary fibrosis is a reparative response characterized by accumulation of extracellular matrix in the lung parenchyma that may be observed in end-stage sarcoidosis. This article will discuss the recent advancements in the understanding of the pathogenesis of pulmonary fibrosis in sarcoidosis in com...

journal_title：Current opinion in pulmonary medicine

authors： Shigemitsu H,Azuma A

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Cystic fibrosis (CF) is a complex genetic disease affecting many organs, although 85% of the mortality is a result of lung disease. The natural history of the lung disease consists of early and persistent infection, an exaggerated inflammatory response, structural airway changes (i.e. bronchiectasis),...

journal_title：Current opinion in pulmonary medicine

authors： Flume PA

更新日期：2011-07-01 00:00:00